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Search Results for " tumor cells "

ターゲット

Apoptosis HDAC

607

阻害剤

118

天然化合物

335

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T2430	HPOB		Apoptosis , HDAC
			Apoptosis , HDAC
T3072	XL019		Apoptosis , FLT , JAK , PDGFR
	XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.		Apoptosis , FLT , JAK , PDGFR
T10425	AZ084		CCR
	AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.		CCR
T2065	Bioymifi	DR5 Activator	Apoptosis , TNF
	Bioymifi (DR5 Activator) is a novel and potent small-molecule activator of the TRAIL receptor DR5 in human cancer cells.		Apoptosis , TNF
T9303	MRTX1133		Ras
	MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.		Ras
T8497	SX-682		CXCR
	SX-682 is a potent, selective and orally bioavailable inhibitor of CXCR1/2 ,has the potential to treat castration-resistant prostate cancer.		CXCR
T2345	PTC-209	PTC209,PTC 209	BMI-1 , Autophagy
	PTC-209 is a potent and selective BMI-1 inhibitor.		BMI-1 , Autophagy
T6540	Ibuprofen Lysine	Neoprofen	COX
	Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.		COX
T21981	Phthalazinone pyrazole		Aurora Kinase
	Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.		Aurora Kinase
T1394	Ibuprofen	Brufen,(±)-Ibuprofe,Motrin,Advil	COX
	Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu...		COX
T12871	Talmapimod	SCIO-469	p38 MAPK
	Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 ...		p38 MAPK
T15249	Estrogen receptor modulator 1		Estrogen Receptor/ERR
	Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.4...		Estrogen Receptor/ERR
T8369	Adagrasib	MRTX849	Ras
	Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib ...		Ras
T11279	FGFR1/DDR2 inhibitor 1		Discoidin Domain Receptor (DDR) , FGFR , Others
	FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.		Discoidin Domain Receptor (DDR) , FGFR , Others
T11571	HLY78	4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine	Wnt/beta-catenin
	HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.		Wnt/beta-catenin
T12134	MYCMI-6	NSC354961	Apoptosis , c-Myc
	MYCMI-6 (NSC-354961) is a potent and selective inhibitor of endogenous MYC:MAX protein interactions，reduces proliferation and induces massive apoptosis in tumor tissue from a MYC-driven xenograft tumor model without seve...		Apoptosis , c-Myc
T2490	Osimertinib	AZD-9291,Mereletinib	EGFR
	Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activi...		EGFR
TQ0059	Ilorasertib	ABT-348	VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
	Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ...		VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
T1083L	Theophylline monohydrate	Quibron	HDAC , PDE , Adenosine Receptor
	Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ...		HDAC , PDE , Adenosine Receptor
T3634	Osimertinib mesylate	Mereletinib mesylate,AZD-9291 mesylate	EGFR
	Osimertinib mesylate (Mereletinib mesylate) is an irreversible and mutant selective EGFR inhibitor (IC50s: 12/1 nM for EGFR(L858R) and EGFR(L858R/T790M)).		EGFR
T8359	Lanreotide acetate	Lanreotide acetate (108736-35-2 free base),BIM 23014 (acetate),BIM 23014 acetate	Others
	Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome		Others
T6178	PTC-209 hydrobromide	PTC-209 HBr	BMI-1 , Autophagy
	PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).		BMI-1 , Autophagy
T10772	Cevipabulin	TTI-237	Microtubule Associated
	Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line).		Microtubule Associated
T4235	Roblitinib	FGF-401	FGFR
	Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads ...		FGFR
T40555L	LyP-1 acetate	LyP-1 acetate (454487-07-1 Free base)	Others
	LyP-1 acetate is a tumor homing peptide specifically binding to p32 receptors overexpressed in various tumor-associated cells.		Others
T28607	Rocepafant	LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730	Platelet aggregation
	Rocepafant (LAU8080) is a platelet-activating factor (PAF) antagonist that attenuates hypoxic-ischemic brain damage in neonatal rats.Rocepafant inhibits tumor necrosis factor-Afa-mediated cytotoxicity in mouse L929 tumor...		Platelet aggregation
T9463	6-HYDROXYLAMINOURACIL		Others
	6-HYDROXYLAMINOURACIL is a derivative of uracil, which induces DNA damage and apoptosis in tumor cells and inhibits tumor cell growth in vitro.		Others
T34602	Selatinib		EGFR
	Selatinib is an orally active and potent dual inhibitor of EGFR and ErbB2 with anticancer activity that inhibits the growth of NCI-N87 tumor cells.		EGFR
T20038	2-Fluoroadenine	NSC-27364,NSC 27364,NSC27364	DNA/RNA Synthesis
	2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.		DNA/RNA Synthesis
T10313	AMXT-1501 tetrahydrochloride		Others
	AMXT-1501 tetrahydrochloride is an inhibitor of polyamine transport. It blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells.		Others
T10792L	CHK1-IN-4 hydrochloride	CHK1-IN-4 hydrochloride（2120398-41-4 Free base）	Chk
	CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1). CHK1-IN-4 hydrochloride potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 hydrochloride has anti-tumor activity.		Chk
T3548	Epacadostat	INCB 024360,IDO Inhibitor 1	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	Epacadostat (INCB 024360) is an oral-available inhibitor of indoleamine 2, 3-dioxygenase (IDO1), increasing the proliferation and activation of various immune cells and reducing tumor-associated regulatory T cells.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T13050	SYP-5		HIF/HIF Prolyl-Hydroxylase , HIF
	SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.		HIF/HIF Prolyl-Hydroxylase , HIF
T3708	BP-1-102		STAT
	BP-1-102 is an orally active, effective and specific STAT3 inhibitor. BP-1-102 binds Stat3 (Kd: 504 nM), then blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 μM), and selectively inhi...		STAT
T12831L	SAR405		PI3K , Autophagy
	SAR-405 is a potent and selective PIK3C3/Vps34 inhibitor (IC50:1.2 nM; Kd:1.5 nM) that prevents autophagy and synergizes with MTOR inhibition in tumor cells. SAR405 treatment also inhibits autophagy induced either by sta...		PI3K , Autophagy
T12344L1	OTS186935 FA	OTS186935 FA（2093400-18-9 Free base）	Histone Methyltransferase
	OTS186935 FA is a protein methyltransferase SUV39H2 inhibitor.OTS186935 FA inhibits tumor growth in MDA-MB-231 breast cancer cells and A549 lung cancer cells.		Histone Methyltransferase
T28865	STAT3-IN-B9	STAT3 IN B9,B9	STAT
	STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.		STAT
T6891	MK-4101		Apoptosis , Hedgehog/Smoothened , Smo
	MK-4101, an effective inhibitor of the Hedgehog pathway, has anti-tumor activity through the induction of extensive apoptosis and inhibition of proliferation in tumor cells.		Apoptosis , Hedgehog/Smoothened , Smo
T13393	ZEN-3411		Epigenetic Reader Domain
	ZEN-3411 is an orally available and potent BET inhibitor that inhibits BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2) and suppresses the growth of tumor cells overproducing BET proteins.		Epigenetic Reader Domain
T6844	GGTI298 Trifluoroacetate	GGTI 298,GGTI 298 TFA salt	Apoptosis , Transferase , Ras
	GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycle and induce apoptosis.		Apoptosis , Transferase , Ras
T10341	Antitumor agent-19		Others
	Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.		Others
T14125	Adarotene	ST1926	Apoptosis
	Adarotene (ST1926) is an effective apoptosis inducer. It surprisingly produces DNA damage and exhibits a potent antiproliferative activity on a large panel of human tumor cells.		Apoptosis
T1408	Capecitabine	Xeloda,Capecitibine,Capiibine,RO 09-1978	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moie...
T77191	Clivatuzumab		Others
	Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good therapeutic effect on a variety of tumor cells.		Others
T6517	Golvatinib	E-7050	VEGFR , c-Met/HGFR
	Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic ...		VEGFR , c-Met/HGFR
T8623	TMIFRY8XAG	1,1'-(4-CHLOROBUTYLIDENE)BIS(4-FLUOROBENZENE),4-oxo-1,4-dihydroquinoline-2-carboxylic acid	Others
	TMIFRY8XAG (4-oxo-1,4-dihydroquinoline-2-carboxylic acid) is a derivative of Zerumbone with potential anti-tumor effects towards HeLa cancer cells.		Others
T3352	XL413		cholecystokinin , Casein Kinase , Pim , CDK
	XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA ...		cholecystokinin , Casein Kinase , Pim , CDK
TD0106	IR-783		Others
	IR 783 is a heptamethine cyanine fluorescent probe for in vivo imaging of tumor cells. It displays excitation/emission maxima of 633/780 nm, respectively.		Others
T17208	USL311		CXCR
	USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing...		CXCR
T2576	Brivanib (alaninate)	BMS-582664,Brivanib Alaninate	VEGFR , FGFR , Autophagy
	Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosi...		VEGFR , FGFR , Autophagy

Compounds

HPOB

T2430

Synonym:

Target: Apoptosis, HDAC

XL019

T3072

Synonym:

Target: Apoptosis, FLT, JAK, PDGFR

Synonym: DR5 Activator

Target: Apoptosis, TNF

Synonym: PTC209,PTC 209

Target: BMI-1, Autophagy

Phthalazinone pyrazole

T21981

Synonym:

Target: Aurora Kinase

Ibuprofen

T1394

Synonym: Brufen,(±)-Ibuprofe,Motrin,Advil

Estrogen receptor modulator 1

T15249

Synonym:

Target: Estrogen Receptor/ERR

FGFR1/DDR2 inhibitor 1

T11279

Synonym:

Target: Discoidin Domain Receptor (DDR), FGFR, Others

HLY78

T11571

Synonym: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine

Target: Wnt/beta-catenin

MYCMI-6

T12134

Synonym: NSC354961

Target: Apoptosis, c-Myc

Osimertinib

T2490

Synonym: AZD-9291,Mereletinib

Target: VEGFR, FLT, c-RET, PDGFR, Aurora Kinase

Theophylline monohydrate

T1083L

Synonym: Quibron

Target: HDAC, PDE, Adenosine Receptor

Osimertinib mesylate

T3634

Synonym: Mereletinib mesylate,AZD-9291 mesylate

Target: EGFR

Lanreotide acetate

T8359

Synonym: Lanreotide acetate (108736-35-2 free base),BIM 23014 (acetate),BIM 23014 acetate

Target: BMI-1, Autophagy

Cevipabulin

T10772

Synonym: TTI-237

Target: Microtubule Associated

Synonym: LyP-1 acetate (454487-07-1 Free base)

Target: Others

Rocepafant

T28607

Synonym: LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730

Target: Platelet aggregation

6-HYDROXYLAMINOURACIL

Synonym: NSC-27364,NSC 27364,NSC27364

Target: DNA/RNA Synthesis

AMXT-1501 tetrahydrochloride

T10313

Synonym:

Target: Others

CHK1-IN-4 hydrochloride

T10792L

Synonym: CHK1-IN-4 hydrochloride（2120398-41-4 Free base）

Target: Chk

Epacadostat

T3548

Synonym: INCB 024360,IDO Inhibitor 1

Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)

SYP-5

T13050

Synonym:

Target: HIF/HIF Prolyl-Hydroxylase, HIF

Target: PI3K, Autophagy

OTS186935 FA

T12344L1

Synonym: OTS186935 FA（2093400-18-9 Free base）

Target: Histone Methyltransferase

STAT3-IN-B9

T28865

Synonym: STAT3 IN B9,B9

Target: Apoptosis, Hedgehog/Smoothened, Smo

ZEN-3411

T13393

Synonym:

Target: Epigenetic Reader Domain

GGTI298 Trifluoroacetate

T6844

Synonym: GGTI 298,GGTI 298 TFA salt

Target: Apoptosis, Transferase, Ras

Synonym: Xeloda,Capecitibine,Capiibine,RO 09-1978

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Target: VEGFR, c-Met/HGFR

TMIFRY8XAG

T8623

Synonym: 1,1'-(4-CHLOROBUTYLIDENE)BIS(4-FLUOROBENZENE),4-oxo-1,4-dihydroquinoline-2-carboxylic acid

Target: cholecystokinin, Casein Kinase, Pim, CDK

Synonym: BMS-582664,Brivanib Alaninate

Target: VEGFR, FGFR, Autophagy

カタログ番号	製品名	別名	ターゲット
T9135	Epirosmanol		Others
	Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa).		Others
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
T3S1416	Decursin	Decursinol angelate,(+)-Decursin	Apoptosis , PKC
	1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ...		Apoptosis , PKC
T7786	Tryptanthrin		DNA gyrase
	Tryptanthrin is a natural DNA gyrase inhibitor.		DNA gyrase
T3673	Mollugin	Rubimaillin	HER , JAK
	Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...		HER , JAK
T2758	Madecassic acid	6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose	Others , TNF , COX , NO Synthase , Interleukin
	Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.		Others , TNF , COX , NO Synthase , Interleukin
T2799	(20S)-Protopanaxadiol	20-Epiprotopanaxadiol,20(S)-APPD	Apoptosis , Reactive Oxygen Species , P-gp
	(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin.		Apoptosis , Reactive Oxygen Species , P-gp
T1511	Daunorubicin hydrochloride	Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin	Apoptosis , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic , Autophagy
	Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.
T3402	20(S)-Ginsenoside Rg3	20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3	EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
	20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
TN2213	Imperialine 3-β-D-glucoside	Sipeimine-3-beta-D-glucoside	Others
	Imperialine 3-β-D-glucoside (Sipeimine-3-beta-D-glucoside) is a natural product. Imperialine 3-β-D-glucoside may exhibit anti-tumor properties against multi-drug resistant tumor cells.		Others
T3S1967	(S)-Indoximod	N-ME-Tryptophan,Abrine,L-Abrine	Others , Indoleamine 2,3-Dioxygenase (IDO)
	(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...		Others , Indoleamine 2,3-Dioxygenase (IDO)
TN2182	Sarracenin		Others
	Sarracenin is a natural product. Sarracenin shows cytotoxic activities against tumor cells.		Others
T2907	Tanshinone I	Tanshinone A	Phospholipase
	Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.		Phospholipase
T2S0886	Terrestrosin D		Apoptosis , Others
	Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of action...		Apoptosis , Others
TQ0089	Juglanin		Apoptosis , JNK , Autophagy
	Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.		Apoptosis , JNK , Autophagy
T3S1513	(20R)-Protopanaxadiol	Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol	Others , Antibacterial
	1. (20R)-Protopanaxadiol ((20R)-Protopanaxdiol) has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial microvascular density and its proliferation activity, improving...		Others , Antibacterial
T3395	Timosaponin AIII	Filiferin B,AneMarsaponin A3,Timosaponin A3	AChE , mTOR
	Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC...		AChE , mTOR
T7990	9-hydroxy-4-androstene-3,17-dione		Others
	9-hydroxy-4-androstene-3,17-dione is a steroid hormone. It has anti-tumor activity and can inhibit the growth of many types of cancer cells, including breast, prostate and lung cancer cells.		Others
T8852	Tubuloside B		Apoptosis , Others
	The neuroprotective effect of tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, on tumor necrosis factor-alpha (TNFalpha)-induced apoptosis in SH-SY5Y neuronal cells.		Apoptosis , Others
T2S0389	Emodin-1-O-β-D-glucopyranoside	Emodin-1-O-glucoside	Others
	1. Emodin-1-O-β-D-glucopyranoside (Emodin-1-O-glucoside) has neuroprotective and uncoupling activities, and that it may be the a new uncoupler of nNOS-PSD-95. 2. Emodin-1-O-β-D-glucopyranoside shows inhibitory effects on...		Others
TN1141	Isodeoxyelephantopin		NF-κB , Reactive Oxygen Species , Autophagy
	Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibit...		NF-κB , Reactive Oxygen Species , Autophagy
T7984	2-Hydroxyflavanone		Others
	2-Hydroxyflavanone is a naturally occurring flavonoid found in many plants and fruits. It has antioxidant, anti-inflammatory and anti-tumor activity, scavenging free radicals, reducing inflammation and inhibiting the gro...		Others
T10021	1-Methylxanthine		Endogenous Metabolite
	1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.		Endogenous Metabolite
T21494	Oligomycin		HIF
	Oligomycin is an antifungal antibiotic that is an inhibitor of H+-ATP synthetase. The Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibited HIF-1alpha expression in hypoxic tu...		HIF
TN1516	Cnidicin		NOS , NO Synthase
	Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr...		NOS , NO Synthase
TN7052	Crocin III	Crocetin-mono-(β-D-gentiobiosyl)-ester	Others
	Crocin III (Crocetin-mono-(β-D-gentiobiosyl)-ester) is a crocin derived from saffron (Crocus sutivus L.). Crocins inhibit the cell growth of tumor cells and have anti-inflammatory activity.		Others
T5282	5-Methyluridine	Ribothymidine,Thymine riboside	Others , Endogenous Metabolite
	5-Methyluridine (Thymine riboside) is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethy...		Others , Endogenous Metabolite
T3314	Perillyl alcohol	Isocarveol,Perilla alcohol	Apoptosis , Endogenous Metabolite
	Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol (Isocarveol) inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-...		Apoptosis , Endogenous Metabolite
T1086	Vitamin D2	Calciferol,Ergocalciferol,Ercalciol	DNA/RNA Synthesis , Endogenous Metabolite
	Ergocalciferol (Vitamin D2 (Calciferol)) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond with a strong inhibitory effect against bladder tumor promotion by sodium saccharin, and it in...		DNA/RNA Synthesis , Endogenous Metabolite
T5715	(E)-Flavokawain A	FLAVOKAVAIN A(P)	Apoptosis , P450
	(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.		Apoptosis , P450
T6S0119	Dauricine		Apoptosis , Others , NF-κB
	1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...		Apoptosis , Others , NF-κB
T0650	Phenyl acetate	Acetylphenol,Phenol acetate,Acetic acid phenyl ester	Others , Endogenous Metabolite
	Phenyl acetate (Acetic acid phenyl ester) is an aromatic fatty acid metabolite of phenylalanine with potential antineoplastic activity. Naturally occurring in mammals, phenylacetate induces differentiation, growth inhibi...		Others , Endogenous Metabolite
T3380	Homoharringtonine	Myelostat,Ceflatonin,HHT,Omacetaxine mepesuccinate	STAT
	Homoharringtonine (HHT) is a natural alkaloid that inhibits the translation of proteins and is cytotoxic. Homoharringtonine acts on the ribosomes of tumor cells to inhibit the elongation step of protein translation, ther...		STAT
TN6714	Geranylgeraniol	FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095	Apoptosis
	Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ...		Apoptosis
TN1440	Beta-Hydroxyisovalerylshikonin		EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
	Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
T3674	Hydroxysafflor yellow A	HSYA,Safflomin A	TGF-beta/Smad
	Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacit...		TGF-beta/Smad
TN1163	2'-Hydroxychalcone		Others
	2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxyc...		Others
T3S1955	7-Ethylcamptothecin		Others
	1. 7-Ethylcamptothecin has the superior antitumor activity than CPT. (a). 7-Ethylcamptothecin has a stronger growth-inhibiting activity against tumor cells. (b). 7-Ethylcamptothecin remains in the intestinal tract for a ...		Others
TN1620	Eriocalyxin B		Apoptosis , cAMP , NF-κB , STAT
	Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inh...		Apoptosis , cAMP , NF-κB , STAT
T2897	(Rac)-Shikonin	(±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid	Others
	(Rac)-Shikonin (Anchusin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics,...		Others
TN1557	Decursinol angelate		ERK , VEGFR , PKC , JNK
	Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion an...		ERK , VEGFR , PKC , JNK
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T3604	Sodium dichloroacetate	Sodium Dichloroacetate,DCA,bichloroacetic acid,Sodium dichloroacetate (DCA)	Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK
	Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion chann...		Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK
T7961	N4-Benzoyl-2′-deoxycytidine		Others
	N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase. In vitro studies have shown that it inhibits replication in viruses, b...		Others
T2P2806	Hederacolchiside A1	Raddeanoside R13	Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
	Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...		Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
T1257	Bestatin	Ubenimex	Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
	Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin...		Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
T6718	Zingerone	Gingerone,Vanillylacetone,NSC 15335	NF-κB
	Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antidiarrhoeic, antilipolytic, antispasmodic and anti-tumor properties. Zingerone(Gi...		NF-κB
T4958	(-)-Alkannin	Alkannin,Shikonin	Apoptosis , PI3K
	(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, a...		Apoptosis , PI3K
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T3S2344	β,β-Dimethylacrylshikonin	Dimethylacrylshikonin,β, β-Dimethylacrylshikonin	ERK , HIF/HIF Prolyl-Hydroxylase
	1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...		ERK , HIF/HIF Prolyl-Hydroxylase
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天然物製品

Synonym: Flavokavain A

Target: Apoptosis, p38 MAPK

Decursin

T3S1416

Synonym: Decursinol angelate,(+)-Decursin

Target: Apoptosis, PKC

Synonym: 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose

Target: Others, TNF, COX, NO Synthase, Interleukin

(20S)-Protopanaxadiol

T2799

Synonym: 20-Epiprotopanaxadiol,20(S)-APPD

Target: Apoptosis, Reactive Oxygen Species, P-gp

Daunorubicin hydrochloride

T1511

Synonym: Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin

Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic, Autophagy

20(S)-Ginsenoside Rg3

T3402

Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3

Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite

Imperialine 3-β-D-glucoside

TN2213

Synonym: Sipeimine-3-beta-D-glucoside

Target: Others

(S)-Indoximod

T3S1967

Synonym: N-ME-Tryptophan,Abrine,L-Abrine

Target: Others, Indoleamine 2,3-Dioxygenase (IDO)

Synonym: Tanshinone A

Target: Phospholipase

Terrestrosin D

T2S0886

Synonym:

Target: Apoptosis, Others

Juglanin

TQ0089

Synonym:

Target: Apoptosis, JNK, Autophagy

(20R)-Protopanaxadiol

T3S1513

Synonym: Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol

Target: Others, Antibacterial

Timosaponin AIII

T3395

Synonym: Filiferin B,AneMarsaponin A3,Timosaponin A3

Target: AChE, mTOR

9-hydroxy-4-androstene-3,17-dione

Target: Apoptosis, Others

Emodin-1-O-β-D-glucopyranoside

T2S0389

Synonym: Emodin-1-O-glucoside

Target: NF-κB, Reactive Oxygen Species, Autophagy

Target: Endogenous Metabolite

Target: NOS, NO Synthase

Crocin III

TN7052

Synonym: Crocetin-mono-(β-D-gentiobiosyl)-ester

Target: Others

5-Methyluridine

T5282

Synonym: Ribothymidine,Thymine riboside

Target: Others, Endogenous Metabolite

Perillyl alcohol

T3314

Synonym: Isocarveol,Perilla alcohol

Target: Apoptosis, Endogenous Metabolite

Vitamin D2

T1086

Synonym: Calciferol,Ergocalciferol,Ercalciol

Target: DNA/RNA Synthesis, Endogenous Metabolite

(E)-Flavokawain A

T5715

Synonym: FLAVOKAVAIN A(P)

Target: Apoptosis, P450

Dauricine

T6S0119

Synonym:

Target: Apoptosis, Others, NF-κB

Phenyl acetate

T0650

Synonym: Acetylphenol,Phenol acetate,Acetic acid phenyl ester

Target: Others, Endogenous Metabolite

Homoharringtonine

T3380

Synonym: Myelostat,Ceflatonin,HHT,Omacetaxine mepesuccinate

Target: STAT

Geranylgeraniol

TN6714

Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095

Target: Apoptosis

Beta-Hydroxyisovalerylshikonin

TN1440

Synonym:

Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase

Hydroxysafflor yellow A

T3674

Synonym: HSYA,Safflomin A

Target: TGF-beta/Smad

Target: Apoptosis, cAMP, NF-κB, STAT

(Rac)-Shikonin

T2897

Synonym: (±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid

Target: ERK, VEGFR, PKC, JNK

Cytochalasin D

T3229

Synonym:

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Sodium dichloroacetate

T3604

Synonym: Sodium Dichloroacetate,DCA,bichloroacetic acid,Sodium dichloroacetate (DCA)

Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK

N4-Benzoyl-2′-deoxycytidine

Synonym: Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

Bestatin

T1257

Synonym: Ubenimex

Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR

Zingerone

T6718

Synonym: Gingerone,Vanillylacetone,NSC 15335

Target: NF-κB

(-)-Alkannin

T4958

Synonym: Alkannin,Shikonin

Target: Apoptosis, PI3K

Oroxylin A

T6S1315

Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

β,β-Dimethylacrylshikonin

T3S2344

Synonym: Dimethylacrylshikonin,β, β-Dimethylacrylshikonin

Target: ERK, HIF/HIF Prolyl-Hydroxylase

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00603	TL1A/TNFSF15 Protein, Mouse, Recombinant	Mouse	E. coli
	Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant	Rabbit	E. coli
	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty...
TMPK-00782	PLAU/uPA Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-00176	BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (...
TMPY-01964	CD16a Protein, Human, Recombinant (F176V, His)	Human	HEK293 Cells
	The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also ...
TMPK-00305	TGFBR1 Protein, Human, Recombinant (mFc & Avi)	Human	HEK293 Cells
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPJ-01464	IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)	Human	HEK293 Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m...
TMPK-00807	Osteopontin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration ...
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66...
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli)	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-05030	PCDH7 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cance...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPY-04329	Vimentin Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers ...
TMPY-02153	TNF beta Protein, Human, Recombinant	Human	E. coli
	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPY-03382	FGF-6 Protein, Human, Recombinant	Human	E. coli
	FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi...
TMPJ-00249	TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated	Human	HEK293 Cells
	Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPJ-00090	FGF-9 Protein, Human, Recombinant	Human	E. coli
	Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inc...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPJ-00994	LTBR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce...
TMPY-00365	GALNT7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either ...
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ...
TMPY-01280	FOLR2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant ...
TMPY-01442	DMBT1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d...
TMPY-00021	PADI4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPJ-00137	APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea...
TMPY-01061	FGF-10 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-02030	CD82 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras...
TMPY-01890	CLIC4 Protein, Human, Recombinant (His)	Human	E. coli
	Chloride intracellular channel protein 4, also known as Intracellular chloride ion channel protein p64H1 and CLIC4, is a member of the chloride channel CLIC family. It contains oneGST C-terminal domain. CLIC4 is a mem...
TMPK-00091	NKp30/NCR3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates N...
TMPK-00063	OX40L/TNFSF4 Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of de...
TMPH-03297	LGALS3BP Protein, Rat, Recombinant (His)	Rat	E. coli
	Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
TMPK-00188	JAM-A Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor mi...
TMPK-01381	CSPG4/MCSP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The chondroitin sulfate proteoglycan-4 (CSPG4) is a cell surface proteoglycan overexpressed in a huge range of human and canine neoplastic lesions by tumor cells, tumor microenvironment and cancer initiating cells. CSPG4...
TMPY-02402	WTAP Protein, Human, Recombinant (GST)	Human	E. coli
	Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identif...
TMPK-00130	LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3.This protein ha...
TMPY-00193	ULBP-4 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The expressions of both RAET1E2 transcripts and protein can be found in different tumor cells and tissues. ULBP-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molec...
TMPJ-00145	4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to ...
TMPK-00090	NKp30/NCR3 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates N...
TMPY-00194	ULBP-4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The expressions of both RAET1E2 transcripts and protein can be found in different tumor cells and tissues. ULBP-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molec...
TMPK-00340	ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPY-02597	IL-37 Protein, Human, Recombinant	Human	E. coli
	Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the e...
TMPK-00260	CD155/PVR Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells...
TMPK-00539	PLAU/uPA Protein (active form), Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-00783	PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-00339	ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-00341	ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
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TL1A/TNFSF15 Protein, Mouse, Recombinant

TMPJ-00603

Species: Mouse

Expression System: E. coli

TNF alpha Protein, Rabbit, Recombinant

TMPJ-00779

Species: Rabbit

Expression System: E. coli

PLAU/uPA Protein, Mouse, Recombinant (His & Avi)

TMPK-00782

Species: Mouse

Expression System: HEK293 Cells

BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)

TMPK-00176

Species: Human

Expression System: HEK293 Cells

CD16a Protein, Human, Recombinant (F176V, His)

TMPY-01964

Species: Human

Expression System: HEK293 Cells

TGFBR1 Protein, Human, Recombinant (mFc & Avi)

TMPK-00305

Species: Human

Expression System: HEK293 Cells

IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

TMPJ-01464

Species: Human

Expression System: HEK293 Cells

Osteopontin Protein, Mouse, Recombinant (His)

TMPK-00807

Species: Mouse

Expression System: HEK293 Cells

CEACAM3 Protein, Human, Recombinant (His)

TMPY-01850

Species: Human

Expression System: HEK293 Cells

IFN gamma Protein, Human, Recombinant (E. coli)

TMPY-06983

Species: Human

Expression System: E. coli

PCDH7 Protein, Human, Recombinant (His)

TMPY-05030

Species: Human

Expression System: Baculovirus Insect Cells

TPSAB1 Protein, Human, Recombinant (His)

TMPJ-01204

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

TMPJ-01465

Species: Human

Expression System: E. coli

Granzyme B/GZMB Protein, Human, Recombinant (His)

TMPY-00817

Species: Human

Expression System: HEK293 Cells

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

Vimentin Protein, Human, Recombinant (His)

TMPY-04329

Species: Human

Expression System: Baculovirus Insect Cells

TNF beta Protein, Human, Recombinant

TMPY-02153

Species: Human

Expression System: E. coli

FGF-6 Protein, Human, Recombinant

TMPY-03382

Species: Human

Expression System: E. coli

TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

TMPJ-00249

Species: Human

Expression System: HEK293 Cells

FGF-9 Protein, Human, Recombinant

TMPJ-00090

Species: Human

Expression System: E. coli

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

TMPJ-00662

Species: Human

Expression System: E. coli

LTBR Protein, Mouse, Recombinant (hFc)

TMPJ-00994

Species: Mouse

Expression System: HEK293 Cells

GALNT7 Protein, Human, Recombinant (His)

TMPY-00365

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

TMPJ-01467

Species: Human

Expression System: E. coli

FOLR2 Protein, Human, Recombinant (His)

TMPY-01280

Species: Human

Expression System: HEK293 Cells

DMBT1 Protein, Human, Recombinant (His)

TMPY-01442

Species: Human

Expression System: HEK293 Cells

PADI4 Protein, Human, Recombinant (His)

TMPY-00021

Species: Human

Expression System: Baculovirus Insect Cells

VEGF121 Protein, Human, Recombinant (His)

TMPJ-00865

Species: Human

Expression System: HEK293 Cells

APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)

TMPJ-00137

Species: Human

Expression System: HEK293 Cells

FGF-10 Protein, Human, Recombinant

TMPY-01061

Species: Human

Expression System: E. coli

CD82 Protein, Human, Recombinant (His)

TMPY-02030

Species: Human

Expression System: HEK293 Cells

CLIC4 Protein, Human, Recombinant (His)

TMPY-01890

Species: Human

Expression System: E. coli

NKp30/NCR3 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00091

Species: Human

Expression System: HEK293 Cells

OX40L/TNFSF4 Trimer Protein, Human, Recombinant (His & Flag)

TMPK-00063

Species: Human

Expression System: HEK293 Cells

LGALS3BP Protein, Rat, Recombinant (His)

TMPH-03297

Species: Rat

Expression System: E. coli

JAM-A Protein, Mouse, Recombinant (His)

TMPK-00188

Species: Mouse

Expression System: HEK293 Cells

CSPG4/MCSP Protein, Cynomolgus, Recombinant (His)

TMPK-01381

Species: Cynomolgus

Expression System: HEK293 Cells

WTAP Protein, Human, Recombinant (GST)

TMPY-02402

Species: Human

Expression System: E. coli

LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)

TMPK-00130

Species: Human

Expression System: HEK293 Cells

ULBP-4 Protein, Human, Recombinant (hFc)

TMPY-00193

Species: Human

Expression System: HEK293 Cells

4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)

TMPJ-00145

Species: Mouse

Expression System: HEK293 Cells

NKp30/NCR3 Protein, Human, Recombinant (His & Avi)

TMPK-00090

Species: Human

Expression System: HEK293 Cells

ULBP-4 Protein, Human, Recombinant (His)

TMPY-00194

Species: Human

Expression System: HEK293 Cells

ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00340

Species: Human

Expression System: HEK293 Cells

IL-37 Protein, Human, Recombinant

TMPY-02597

Species: Human

Expression System: E. coli

CD155/PVR Protein, Human, Recombinant (His & Avi)

TMPK-00260

Species: Human

Expression System: HEK293 Cells

PLAU/uPA Protein (active form), Cynomolgus, Recombinant (His)

TMPK-00539

Species: Cynomolgus

Expression System: HEK293 Cells

PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-00783

Species: Mouse

Expression System: HEK293 Cells

ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-00339

Species: Mouse

Expression System: HEK293 Cells

ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TMPK-00341

Species: Human

Expression System: HEK293 Cells

--------- More ---------

カタログ番号	製品名
L2152	Targeted Therapy Drug Library	119 compounds
	119 tumor-targeted drugs that can be used for high-throughput and high-content screening.
L2100	Anti-Cancer Compound Library	7234 compounds
	A unique collection of 7234 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L2521	Glycolysis Compound Library	555 compounds
	555 glycolysis-related active compounds for high-throughput and high-content screening.
L2140	Cancer Cell Differentiation Compound Library	406 compounds
	A unique collection of 406 cancer cell differentiation inducing compounds for high throughput and high content screening;
L2130	Anti-Cancer Metabolism Compound Library	1268 compounds
	A unique collection of 1268 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS);
L2160	Anti-Cancer Active Compound Library	3188 compounds
	A unique collection of 3188 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L2150	Anti-Cancer Drug Library	3080 compounds
	A unique collection of 3080 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
L1720	Nucleotide Compound Library	334 compounds
	A unique collection of 334 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs;
L2170	Immuno-Oncology Compound Library	449 compounds
	A unique collection of 449 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening；
L2180	Anti-Cancer Compound Library Plus	1468 compounds
	Well-chosen 1468 anti-tumor compounds with unique structures;
L2501	Human Endogenous Metabolite Compound Library Plus	1283 compounds

L2520	Glycometabolism Compound Library	702 compounds
	702 glycometabolism-related comounds, can be used for HTS and HCT;
L2500	Human Endogenous Metabolite Library	499 compounds
	A collection of 499 selected human endogenous metabolites for high throughput and high content screening.
L1100	Protease Inhibitor Library	343 compounds
	A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
L8500	HIF-1 Signaling Pathway Compound Library	1336 compounds
	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；